Qilin pills combined with levofloxacin for asthenospermia accompanied with accessory sex gland infection: a clinical observation.
- Author:
Yong GAO
1
;
Zi WAN
2
;
Xiang-Zhou SUN
2
;
Ya-Feng LIU
2
;
Ya-Dong ZHANG
2
;
Bin OUYANG
2
;
Sheng-Fu CHEN
2
;
Tao ZHENG
2
;
Xin CHEN
2
;
Qi-Yun YANG
2
;
Da-Yu HAN
2
;
Bing YAO
2
;
Chun-Hua DENG
2
;
Xiang-An TU
2
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Asthenozoospermia; complications; drug therapy; Drugs, Chinese Herbal; therapeutic use; Humans; Infertility, Male; drug therapy; Levofloxacin; therapeutic use; Male; Phytotherapy; Reproductive Tract Infections; drug therapy; Treatment Outcome; Young Adult
- From: National Journal of Andrology 2013;19(12):1115-1118
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the efficacy of the combination of Qilin Pills and levofloxacin in the treatment of asthenospermia accompanied with accessory sex gland infection.
METHODSWe randomly assigned 80 asthenospermia patients with accessory sex gland infection to groups 1 and 2 of equal number, the former treated with Qilin Pills + levofloxacin, and the latter with levofloxacin only. Qilin Pills were administered at the dose of 6 g tid for 30 days, and levofloxacin at the dose of 0.5 g qd for 20 days. We obtained semen parameters, including the percentage of progressively motile sperm and peroxidase-positive white blood cell (WBC) count, before and after medication, and compared the clinical effects between the two groups.
RESULTSAll the patients accomplished the clinical trial. The therapeutic effectiveness rates in improving progressive sperm motility were 60% in group 1 and 17.5% in group 2, with statistically significant differences between the two groups (P < 0.05). As for the peroxidase-positive WBC count in semen, the effectiveness rates were 87.5% and 82.5%, respectively, with no significant differences between the two groups (P > 0.05).
CONCLUSIONFor the treatment of asthenospermia accompanied with accessory sex gland infection, Qilin Pills combined with levofloxacin is evidently better than levofloxacin alone in improving sperm motility, and it has no obvious adverse effects.