Changes in the ultrastructure of sperm flagella in severe idiopathic asthenospermia patients: observation of 22 cases.
- Author:
Qian LIN
1
;
Wen-Jun BAI
2
;
Shu-Ying ZHENG
3
;
Chong GENG
4
;
Xiao-Feng WANG
2
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Asthenozoospermia; pathology; Humans; Male; Sperm Tail; ultrastructure
- From: National Journal of Andrology 2014;20(2):156-159
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the ultrastructural changes of sperm flagella in patients with severe idiopathic asthenospermia.
METHODSUsing the transmission electron microscope, we examined the ultrastructure of sperm flagella from 22 patients with severe idiopathic asthenospermia.
RESULTSUltrastructural anomalies were found in all the 22 patients, 6 with partial or complete absence of internal and external dynamic arms in dedicative of primary ciliary dyskinesia, 1 with hyperplasia, hypertrophy and disordered organization of the fibrous sheath usually referred to as dysplasia of the fibrous sheath, and the other 15 with non-specific flagellar anomalies.
CONCLUSIONExamination of the ultrastructure of sperm flagella in severe idiopathic asthenospermia patients can help to distinguish congenital from acquired flagellar structural anomalies and give valuable guidance in the treatment.