Categories and characteristics of BPH drug evaluation models: a comparative study.
- Author:
Dong-Yan HUANG
1
;
Jian-Hui WU
2
;
Zu-Yue SUN
2
Author Information
1. Pharmacy School of Fudan University, Shanghai 201203, China. hdy043@163.com
2. Department of Pharmacology and Toxicology, Shanghai Institute of Planned Parenthood Research, National Evaluation Center for Toxicology of Fertility Regulation Drugs, Shanghai 200032, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Disease Models, Animal;
Drug Design;
Drug Evaluation;
Male;
Prostatic Hyperplasia;
drug therapy
- From:
National Journal of Andrology
2014;20(2):181-185
- CountryChina
- Language:Chinese
-
Abstract:
Benign prostatic hyperplasia (BPH) is a worldwide common disease in men over 50 years old, and the exact cause of BPH remains largely unknown. In order to elucidate its pathogenesis and screen effective drugs for the treatment of BPH, many BPH models have been developed at home and abroad. This article presents a comprehensive analysis of the categories and characteristics of BPH drug evaluation models, highlighting the application value of each model, to provide a theoretical basis for the development of BPH drugs.
