Surgical treatment of penile Paget's disease: a report of 10 cases.

Xiao-yun XU; Ning Shao; Di Qiao; Quan LI; Chang-jun Yin; Li-xin Hua; Yi Ding; Ning-hong Song

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Surgical treatment of penile Paget's disease: a report of 10 cases.

Author: Xiao-Yun XU ¹ ; Ning SHAO ² ; Di QIAO ² ; Quan LI ³ ; Chang-Jun YIN ³ ; Li-Xin HUA ³ ; Yi DING ² ; Ning-Hong SONG ³
Author Information

1. Department of Dermatology, Jiangsu Provincial Government Hospital, Nanjing, Jiangsu 210024, China.
2. Department of Urology, Jiangsu Provincial Government Hospital, Nanjing, Jiangsu 210024, China.
3. Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Publication Type:Journal Article
MeSH: Adult; Aged; Follow-Up Studies; Humans; Male; Middle Aged; Paget Disease, Extramammary; surgery; Penile Neoplasms; surgery; Retrospective Studies; Treatment Outcome
From: National Journal of Andrology 2014;20(1):54-58
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo investigate the clinical characteristics and surgical treatment of penile Paget's disease.
METHODSWe retrospectively analyzed the treatment and follow-up data of 10 cases of penile Paget's disease surgically treated in Jiangsu Provincial Government Hospital and Jiangsu Provincial People's Hospital from 2008 to 2012.
RESULTSAll the 10 patients received expanded local resection of the lesion with reconstruction of the defects with scrotal skin flaps or free skin flaps from the thigh. All surgeries were successful and the postoperative course was uneventful with complete graft survival and no lymph node metastasis. IIEF scores obtained before and 1 -2 months after surgery showed no statistically significant differences in the penile erectile function (P = 0.229), sexual orgasm (P = 0.761), and sexual satisfaction (P = 0.801) of the patients.
CONCLUSIONWhen penile skin lesions suggest the possibility of Paget's disease, biopsy should be performed and surgery should follow as soon as possible. The ideal surgical option is expanded local resection of the lesion with reconstruction of the defects with scrotal skin flaps or free flaps according to the patient's specific conditions.