Genetic polymorphism of 9 Y-STR loci with short fragment size alleles in unrelated male individuals from Zhuang ethnic group.
- Author:
Qian LI
1
;
Su-Qing GAO
;
Heng-Cong LI
;
Da-Ming WANG
;
Jian-Qiang ZENG
;
Zhi-Hui DENG
Author Information
1. Shenzhen Blood Center, Shenzhen 518035, Guangdong Province, China.
- Publication Type:Journal Article
- MeSH:
Alleles;
China;
ethnology;
Chromosomes, Human, Y;
genetics;
Genetic Loci;
genetics;
Humans;
Male;
Microsatellite Repeats;
genetics;
Polymorphism, Genetic
- From:
Journal of Experimental Hematology
2008;16(3):694-698
- CountryChina
- Language:Chinese
-
Abstract:
The aim of this study was to investigate the genetic polymorphism of Y-chromosome specific short tandem repeat (Y-STR) loci in Zhuang ethnic group of China. Nine Y-STR loci were amplified by single multiplex and the PCR products were detected by using ABI Prism(TM) 3100 DNA Sequencer. The allele frequencies and haplotype frequencies at 9 Y-STR loci were determined in a total of 85 unrelated male individuals from Zhuang ethnic group of China. The results indicated that in the 85 unrelated male individuals, except for the DYS426 locus with a low GD value, the GD values for other 8 Y-STR loci ranged from 0.4387 to 0.8129. A total of 70 haplotypes at 9 Y-STR loci were found, the haplotype diversity was 0.9926. It is concluded that the haplotype polymorphism of 9 Y-STR loci are highly polymorphic in Zhuang ethnic group and also significantly different from our previous reported data of unrelated male individnals in southern Chinese Han population.
