Detection of free testosterone in the serum and semen of idiopathic oligospermia patients and its significance.
- Author:
Guohong WANG
1
;
Ruiji XU
;
Zhongshu ZHANG
;
Xiaojie WANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Case-Control Studies; Humans; Male; Middle Aged; Oligospermia; blood; metabolism; Semen; chemistry; Testosterone; blood; metabolism
- From: National Journal of Andrology 2004;10(9):684-685
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo detect free testosterone (FT) in the serum and semen of patients with idiopathic oligospermia, and further analyze the relationship between FT and idiopathic oligospermia.
METHODSBlood samples were collected from the males of a normal control group (n = 44) and an idiopathic oligospermia group (n = 44) at 8:00-10:00 a.m.. Semen samples were collected from the males of a normal control group (n = 30) and an idiopathic oligospermia group (n = 37) at the same time. Sperm density was detected by routine semen analysis, and FT in the serum and semen was detected by RIA.
RESULTSThere was no significant difference in the serum concentrations of FT between the groups of normal control [(97.50 +/- 46.96) pmol/L] and idiopathic oligospermia [(94.88 +/- 42.04) pmol/L], P > 0.5. But the difference was significant in the semen concentrations of FT between the groups of normal control [(2.01 +/- 0.32) pmol/L] and idiopathic oligospermia [(0.52 +/- 0.44) pmol/L], P < 0.01.
CONCLUSIONMeasurement of semen FT concentration could early reflect the function of the testis, which contributes to the early diagnosis and treatment of idiopathic oligospermia.
