Diabetic damage to male reproduction and its mechanism.
- Author:
Hongguang ZHAO
1
;
Chunnan PIAO
;
Shouliang GONG
Author Information
1. Key Laboratory of Radiobiology of the Ministry of Health, School of Public Health, Jilin University, Changchun, Jilin 130021, China.
- Publication Type:Journal Article
- MeSH:
Androgen-Binding Protein;
biosynthesis;
Animals;
Diabetes Mellitus;
pathology;
physiopathology;
Free Radicals;
Humans;
Leydig Cells;
metabolism;
Male;
Oxidative Stress;
Rats;
Sertoli Cells;
secretion;
Testis;
pathology;
Testosterone;
biosynthesis
- From:
National Journal of Andrology
2004;10(10):767-770
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes is a metabolic disease caused by complicated factors, and its damage to the male reproductive system is threatening men's health. This article reviews the pathophysiological changes in the diabetes-damaged male reproductive system and the mechanism of these changes. Oxidative stress induced by hyperglycemia plays an important role in working damage to the reproductive system of diabetic males, for which some anti-oxidative substances may prove to be an effective cure.