Congenital absence of the vas deferens.
- Author:
Di QIAO
1
;
Hongfei WU
Author Information
1. Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.
- Publication Type:Journal Article
- MeSH:
Cystic Fibrosis;
etiology;
Humans;
Infertility, Male;
etiology;
Male;
Mesonephros;
abnormalities;
Urogenital Abnormalities;
diagnosis;
epidemiology;
therapy;
Vas Deferens;
abnormalities
- From:
National Journal of Andrology
2004;10(10):775-780
- CountryChina
- Language:Chinese
-
Abstract:
Congenital absence of the vas deferens (CAVD) is an important factor that contributes to obstructive azoospermia and male infertility. The etiology of CAVD is associated with the cystic fibrosis transmembrane conductance regulator (CFTR) gene and defects in the Wolffian duct, and frequently complicated by renal agenesis and other urogenital abnormalities. Physical examination may reveal nonpalpable scrotal vas deferentia, while vasography intrinsic vasal absence. Ultrasound and computerized tomography (CT) can rule out the abnormalities of the upper urinary tracts and the seminal vesicles. Although it is difficult to cure the disease, it is now possible for CAVD patients to father children with the help of assisted reproductive technology (ART). The present review is focused on the etiology, diagnosis and treatment of CAVD.
