Differentially expressed genes in prostate cancer and benign prostatic hyperplasia.
- Author:
Tong ZHANG
1
;
Yong XU
;
Hua TANG
;
Min LIU
;
Dalin REN
;
Yuanjie NIU
Author Information
- Publication Type:Journal Article
- MeSH: Down-Regulation; Gene Expression Profiling; Humans; Male; Oligonucleotide Array Sequence Analysis; Prostatic Hyperplasia; genetics; metabolism; Prostatic Neoplasms; genetics; metabolism; Up-Regulation
- From: National Journal of Andrology 2004;10(12):897-899
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo detect and analyze the differentially expressed genes in prostate cancer (PCa) and benign prostatic hyperplasia (BPH).
METHODSOligonucleotide microarray containing 465 genes was used to investigate the differentially expressed genes in PCa and BPH.
RESULTSThere were 35 differentially expressed genes between PCa and BPH, of which 17 were up-regulated and 18 down-regulated in PCa.
CONCLUSIONThe study of the differentially expressed genes in PCa and BPH should help to understand the molecular mechanism of PCa and identify the markers for diagnostic and therapeutic use.
