Measurement of uric acid of seminal plasma in fertile and infertile males.
- Author:
Kaisheng XU
1
;
Xuejun SHANG
;
Yonggang CHEN
;
Feng ZHAO
;
Peiyuan ZHU
;
Yufeng HUANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Azoospermia; metabolism; Case-Control Studies; Humans; Infertility, Male; metabolism; Male; Oligospermia; metabolism; Semen; chemistry; Uric Acid; analysis
- From: National Journal of Andrology 2004;10(12):900-906
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo measure uric acid of seminal plasma in fertile and infertile males.
METHODSOne hundred and sixty-three infertile males were divided into an obstructive azoospermic group (15 cases), a non-obstructive azoospermic group (36 cases), an oligozoospermic group (43 cases), and an asthenozoospermic group (69 cases). Twenty fertile males were included in the control group. Uric acid concentrations of seminal plasma in the fertile and infertile men were assessed by spectrophotometer, and sperm parameters were analyzed by computer-assisted semen analysis (CASA) system.
RESULTSUric acid concentration of seminal plasma in the control group was significantly higher than all the infertile groups (P < 0.01), and that of the obstructive azoospermic group significantly lower than the other infertile groups (P < 0.1), but no significant difference was observed among the other infertile groups (P > 0.05).
CONCLUSIONUric acid may play an important role in male reproduction because of its antioxidative property.