Pre- and post-prostatectomy variation and supplement of sexual hormones in patients with benign prostatic hyperplasia.
- Author:
Xiao-min REN
1
;
Jun YING
;
De-hong YAO
;
Yue-qing JIANG
;
Ming-xi XU
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Aged, 80 and over; Follicle Stimulating Hormone; blood; Gonadal Steroid Hormones; blood; Humans; Luteinizing Hormone; blood; Male; Middle Aged; Prostate-Specific Antigen; blood; Prostatectomy; Prostatic Hyperplasia; blood; drug therapy; surgery; Testosterone; analogs & derivatives; blood; therapeutic use
- From: National Journal of Andrology 2005;11(1):50-55
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the variation of sexual hormones (T and fT) before and after prostatectomy and their post-operative supplement in patients with benign prostatic hyperplasia (BPH).
METHODSSixty-four cases of BPH were randomly divided into a treatment group (Group I, n = 25) and a control group (Group II, n = 39). Plasma LH, FSH, T and fT were measured by radioimmunoassay a week before and two weeks after prostatectomy. After operation, Group I received supplement of testosterone undecanoate, while Group II received none.
RESULTSThe variations of plasma LH, FSH, T and fT were not statistically significant in the two groups before prostatectomy (P > 0.05), but obviously less in Group I than in Group II after operation (P < 0.01).
CONCLUSIONTestosterone supplement is a useful therapy for post-prostatectomy patients with androgen deficiency.
