Quantitative morphometry of hyperplastic hypoechoic nodules in the prostatic outer gland.
- Author:
Xin LI
1
;
Na WANG
;
Huai-Yin SHI
;
Yan ZHANG
;
Xian-Shui FU
;
Jun-Lai LI
;
Jian-Hong XU
;
Jie TANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Biopsy; Epithelium; diagnostic imaging; pathology; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Male; Middle Aged; Muscle, Smooth; diagnostic imaging; pathology; Prostate; diagnostic imaging; pathology; Prostatic Hyperplasia; diagnostic imaging; pathology; Ultrasonography
- From: National Journal of Andrology 2005;11(2):91-93
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the morphotic characteristics of hypoechoic nodules in the outer gland of the prostate with benign
METHODSTwenty-two hyperplastic hypoechoic nodules in the prostatic outer gland were biopsied guided by prostatic hyperplasia. transrectal ultrasound. The hematoxylin-eosin (HE) staining and immunohistochemistry combined with computer assisted quantitative image analyses were adopted to examine the mean percentages of the area densities of stroma, epithelium, glandular lumen and smooth muscle cells.
RESULTSThe area densities of stroma, epithelium, glandular lumen and smooth muscle cells were (72.52 +/- 13.14)%, (20.57 +/- 9.01)%, (6.85 +/- 4.51)% and (24.14 +/- 6.31)%, respectively.
CONCLUSIONHyperplastic hypoechoic nodules may develop in the outer gland as well as in the inner gland of the prostate, but the mean percentages of the components are different between the two kinds of nodules.
