Effect of plasmaslyte A on the liver function of patients undergoing cardiac surgery with extracorporeal circulation.
- Author:
Bin-fei LI
1
;
Xiao-li XIE
;
Zhi-gang ZHANG
;
Zhou CHENG
;
Xiao-zu LIAO
;
Wei-kang LUO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Cardiac Surgical Procedures; Extracorporeal Circulation; Female; Humans; Isotonic Solutions; pharmacology; Liver Function Tests; Male; Middle Aged
- From: Journal of Southern Medical University 2010;30(11):2588-2589
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effect of plasmaslyte A on the liver function of patients receiving cardiac surgery with extracorporeal circulation.
METHODSSixty patients scheduled for cardiac surgery were randomized to receive plasmaslyte A (group P, n=30) and ringer lactate solution (group R, n=30). The two agents were used in priming heart-lung machine and intra- and postoperative crystal solution. All the patients were examined for the levels of AST, ALT and Lac the day before and at 2 h and 1, 3 and 7 days after the surgery. The time of extubation and length of stay at the ICU were record.
RESULTSThe levels of ALT, AST and Lac in group P were significantly lower than those in group R (P<0.05), and the duration of intubation and stay at the ICU was shorter in group P (P<0.05).
CONCLUSIONPlasmaslyte A can markedly reduce the level of AST, ALT and Lac and protect the liver function of patients undergoing cardiac surgery with extracorporeal circulation.
