Effect of obstructive sleep apnea hypopnea syndrome on arterial stiffness.
- Author:
Chao-yang WEN
1
;
Yi-sha TONG
;
Min LI
;
Yu-zhu LI
;
Yu-sheng ZHAO
;
Bin HAN
;
Wei-min LI
;
Li-xin XIE
;
Jie TANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Ankle Brachial Index; Arteries; physiopathology; Case-Control Studies; Humans; Male; Middle Aged; Sleep Apnea, Obstructive; physiopathology; Vascular Stiffness; Young Adult
- From: Journal of Southern Medical University 2010;30(12):2652-2654
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the effect of obstructive sleep apnea hypopnea syndrome (OSAHS) on brachial-ankle pulse wave velocity (b-aPWV) in untreated diagnosed patients.
METHODSThis study involved 24 consecutive male patients with newly diagnosed untreated OSAHS (aged 39.13±8.31 years) and 22 normal male individuals (aged 39.59±10.86 years) matched for age and body mass index. Carotid and extremities ultrasound were performed in all the subjects, and none of them had atherosclerosis, arterial calcification, or aneurysm. No subject had a history of hypertension, coronary heart disease or stroke. All the subjects underwent arterial stiffness evaluation by means of b-aPWV measurements.
RESULTSThe b-aPWV in OSAHS patients was significantly higher than that in normal subjects (1346.86±123.48 vs 1237.91±84.46, P<0.01), and the rate of positive b-aPWV in OSAHS patients was significantly higher (13/24 vs 1/22, P<0.01).
CONCLUSIONThe value and positive rate of b-aPWV in OSAHS patients are higher than those in normal people, suggesting increased arterial stiffness in OSAHS patients.
