Circulation of wild poliovirus type 1 in Northern Viet Nam during 1991-1994
- Author:
Thanh Hien Nguyen
- Publication Type:Journal Article
- Keywords:
virus
- MeSH:
Poliovirus;
Viruses;
epidemiology
- From:Journal of Preventive Medicine
1998;8(1):32-37
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
From 1991 to 1994, 203 poliovirus positive cases were identified among 559 patients with acute flaccid paralysis. Of these 207 isolates: 175 cases were caused by poliovirus type 1, 7 by type 2 and 11 type 3. Most of these isolates were intratypically differentiated by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Of the studied 142 isolates: 107 were wild type 1 poliovirus strains, 7 were wild type 3 poliovirus strains, the remaining strains were Sabin vaccine-like strains. 107 wild type 1 poliovirus strains were divided into 7 groups by PCR-RFLP patterns and were also classified into 3 genomic groups by nucleotide sequencing and phylogenetic analysis. There were 3 unique wild poliovirus strains were circulating in Northern Vietnam during period 1991-1993. In 1994, no wild poliovirus was isolated
