Risk factors of postoperative intravesical recurrence of transitional cell carcinoma of the ureter.
- Author:
Yunlin YE
1
;
Zike QIN
;
Jun BIAN
;
Mingkun CHEN
;
Yanping HUANG
;
Xiaoxu YUAN
;
Xiangzhou SUN
;
Yuping DAI
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Carcinoma, Transitional Cell; pathology; surgery; Causality; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Regression Analysis; Retrospective Studies; Risk Factors; Ureteral Neoplasms; pathology; surgery; Urinary Bladder Neoplasms; pathology
- From: Journal of Southern Medical University 2012;32(4):557-559
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo define the clinicopathological risk factors of intravesical recurrence of primary transitional cell carcinoma of the ureter after surgical intervention.
METHODSPatients with primary carcinoma of the ureter treated between January 2000 and December 2010 were retrospectively analyzed. The intravesical recurrence-free survival rate was calculated using Kaplan-Meier method. Multivariate analysis was conducted with Cox's regression.
RESULTSA total of 104 patients were enrolled, who were followed up for a median of 46 months (13-89 months). Thirty-nine of the patients showed postoperative intravesical recurrence. Urine exfoliative cytology (P=0.000), number of tumors (P=0.006), tumor grade (P=0.039) and co-existence of bladder tumor (P=0.014) were found to independently influence the postoperative intravesical recurrence. Patients with more risk factors had poorer intravesical recurrence-free survival.
CONCLUSIONUrine exfoliative cytology, number of tumors, tumor grade and co-existence of bladder tumor are independent risk factors for postoperative intravesical recurrence of primary transitional cell carcinoma of the ureter. Close follow-up and rigorous treatment are essential for patients with high risk factors.
