Reliability and accuracy of arcuate fasciculus navigation: analysis of 43 cases.
- Author:
Jiashu ZHANG
1
;
Xiaolei CHEN
;
Yan ZHAO
;
Fangye LI
;
Gang ZHENG
;
Jinjiang LI
;
Ting ZHANG
;
Shen HU
;
Bainan XU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Diffusion Tensor Imaging; Female; Humans; Language Disorders; diagnosis; Male; Middle Aged; Nerve Fibers; Neuronavigation; Reproducibility of Results; Young Adult
- From: Journal of Southern Medical University 2012;32(5):601-605
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the reliability and accuracy of arcuate fasciculus (AF) navigation for AF localization and reconstruction.
METHODSReconstruction of the AF and assessment of the aphasia quotient (AQ) were performed in 43 cases before and after surgical removal of lesions in the language area of the brain. The minimal distance between the AF and the lesion (D(1)), preoperative AQ (AQ(1)), the minimal distance between the AF and the surgical cavity (D(2)), and the postoperative AQ (AQ(2)) were measured. Linear correlation analysis was conducted between D(1) or D(2) and the corresponding AQ(1) or AQ(2) to assess the relationship between the AF and language function. The language function of each patient was evaluated postoperatively.
RESULTSThe AF was successfully reconstructed in all the cases. The tractography results of the identical AF generated by 3 different users showed good congruency. A positive linear correlation was demonstrated between D(1) and AQ(1) (P<0.001) and between D(2) and AQ(2) (P=0.001). Only two patients (4.7%) showed language deficits at postoperative follow-up.
CONCLUSIONAF navigation is a reliable and accurate technique for AF reconstruction and localization and helps to preserve the language function after surgical removal of lesions in the language area of the brain.
