Analysis of influencing factors to metastasis in sentinel lymph nodes and non-sentinel lymph nodes in breast cancer.
- Author:
Hui WANG
1
;
Jing WANG
1
;
Ji-dong GAO
1
;
Tie-cheng WU
1
;
Yi FANG
1
;
Xiang WANG
2
Author Information
- Publication Type:Journal Article
- MeSH: Adenocarcinoma, Mucinous; pathology; surgery; Adult; Age Factors; Breast Neoplasms; pathology; surgery; Carcinoma, Ductal, Breast; pathology; surgery; Carcinoma, Intraductal, Noninfiltrating; pathology; surgery; Carcinoma, Lobular; pathology; surgery; Female; Humans; Logistic Models; Lymph Nodes; pathology; surgery; Lymphatic Metastasis; Menopause; Middle Aged; Neoplastic Cells, Circulating; Retrospective Studies; Sentinel Lymph Node Biopsy; Tumor Burden
- From: Chinese Journal of Oncology 2013;35(10):769-772
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the relevant factors influencing sentinel and non-sentinel lymph node (SLNM, NSLNM) metastases in breast cancer.
METHODSThe clinicopathological data of 283 women with breast cancer who underwent sentinel lymph node biopsy from July 2010 to August 2011 in the Cancer Institute and Hospital at Chinese Academy of Medical Sciences were reviewed retrospectively, and the relevant factors affecting sentinel and non-sentinel lymph node metastases were analyzed.
RESULTSUnivariate analysis showed that age, menopause status, tumor size, pathological type and intravascular tumor thrombus were associated with SLNM metastasis (all P < 0.05). Multivariate analysis showed that age, tumor size and intravascular tumor thrombus were associated with SLNM (all P < 0.05) . No risk factors were found in either univariate or multivariate analysis of NSLNM.
CONCLUSIONSAge, tumor size and intravascular tumor thrombus are independent influencing factors associated with SLNM, and age is a protective factor. Whether ER, pathological type and pathological grade are associated with SLNM or not is still controversial.
