Relationship between endogenous hydrogen sulfide and blood stasis syndrome based on the Qi-blood theory of Chinese medicine.
10.1007/s11655-013-1567-7
- Author:
Wei-wei LI
1
;
Hao GUO
;
Xue-mei WANG
Author Information
1. Integrated Laboratory of Chinese and Western Medicine, Peking University First Hospital, Beijing, China.
- Publication Type:Journal Article
- MeSH:
Blood;
metabolism;
Humans;
Hydrogen Sulfide;
metabolism;
Medicine, Chinese Traditional;
Microcirculation;
Qi;
Syndrome
- From:
Chinese journal of integrative medicine
2013;19(9):701-705
- CountryChina
- Language:English
-
Abstract:
"Qi" and "blood" are two essential concepts in Chinese medicine (CM). As qi is intangible, the concept of qi is still controversial between CM and Western medicine. However, the endogenous hydrogen sulfide (H2S) and other gaseous signaling molecules provides a new approach for understanding the essence of qi in CM. Blood stasis syndrome is a common syndrome in CM. According to the CM theory, the incidence of blood stasis syndrome is closely correlated to the reckless movement of qi, as qi and blood are inseparable in regulating physiological functions. In recent years, more and more evidences suggest a close correlation between blood stasis syndrome and microcirculation dysfunction. In this paper, we discuss the relationship between endogenous H2S and blood stasis syndrome based on qi-blood theory of CM. We found that endogenous H2S maybe a material basis in concept of qi in CM, while dysfunctional microcirculation is the pathological basis of the blood stasis syndrome. As qi is closely associated with incidence and progression of blood stasis syndrome, endogenous H2S may play an important role in preventing and treating the blood stasis syndrome by improving the function of microcirculation.
