Chemical constituents from a portion of ethanolicextract of Saussurea lappa roots.
- Author:
Ting ZHANG
1
;
Lin MA
;
Feng WU
;
Ruoyun CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Ethanol; chemistry; Glucosides; chemistry; Lactones; chemistry; Plant Roots; chemistry; Saussurea; chemistry; Sesquiterpenes; chemistry; Sesquiterpenes, Eudesmane; chemistry
- From: China Journal of Chinese Materia Medica 2012;37(9):1232-1236
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study chemical constituents from the roots of Saussurea lappa.
METHODChemical constituents were separated and purified by various techniques such as silica gel column chromatography, Sephadex LH-20 and reversed phase RP-18 column chromatography. Their structures were identified on the basis of spectral data.
RESULTSeventeen compounds were separated and identified as ascleposide E(1), (+)-1-hydroxypinoresinol-4"-O-methyl ester-4'-beta-D-glucopyranoside (2), (+)-1 -hydroxypinoresinol-4"-O-beta-D-glucopyranoside(3), (+)-1-hydroxypinoresinol-1-O-P-D-glucopyranoside (4), phenyl-beta-D-glucopyranoside (5), benzyl-beta-D-glucopyranoside (6), n-butyl-beta-D-glucopyranoside (7), ilicic alcohol (8), beta-cyclocostunolide (9), reynosin (10), 11beta, 13-dihydroreynosin (11), arbusculin A(12), 1beta-hydroxy-arbusculin A (13), santamarin (14), dehydrocostuslactone (15), 11beta, 13-dihydro-3-epizaluzanin C(16)and costunolide (17).
CONCLUSIONCompounds 1-2 were separated from this genus for the first time,and compounds 3,5-7 were separated from this plant for the first time.
