Caffeoylquinic acid derivatives from the seeds of Vernonia anthelmintica.
- Author:
Yongxia WANG
1
;
En WANG
;
Jing SHANG
;
Hao WANG
Author Information
1. Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
chemistry;
Quinic Acid;
analogs & derivatives;
analysis;
chemistry;
isolation & purification;
Seeds;
chemistry;
Vernonia;
chemistry
- From:
China Journal of Chinese Materia Medica
2012;37(11):1590-1592
- CountryChina
- Language:Chinese
-
Abstract:
Mature seeds of Vernonia anthelmintica were separated and purified by using such methods as macroporous absorption resin, Sephadex LH-20 and HPLC preparative chromatography. Six compounds were obtained and their structures were identified by such spectrum techniques as 1H, 13C-NMR and MS. Compound 1-6 were identified as caffeic acid (1), 3-O-caffeoylquinic acid (2), 4-O-caffeoylquinic acid (3), 5-O-caffeoylquinic acid (4), 3, 4-di-O-caffeoylisoquinic acid (5), 3, 4-di-O-caffeoylquinic acid (6). Among them, compounds 1-6 were separated from this plant for the first time, while compounds 3-5 were separated from this genus firstly.
