A Case of Transverse Myelitis Caused by Varicella Zoster Virus in an Immunocompetent Older Patient.
- Author:
Jeong Eun LEE
1
;
Shinwon LEE
;
Kye Hyung KIM
;
Hee Ryeong JANG
;
Young Joo PARK
;
Jin Suk KANG
;
Sung Yong HAN
;
Sun Hee LEE
Author Information
- Publication Type:Case Report
- Keywords: Varicella zoster virus; Transverse myelitis; Immunocompetent; Older patients; Antiviral treatment
- MeSH: Acyclovir; Aged; Chickenpox*; Child; Female; Herpesvirus 3, Human*; Humans; Leg; Magnetic Resonance Imaging; Myelitis, Transverse*; Polymerase Chain Reaction; Spine
- From:Infection and Chemotherapy 2016;48(4):334-337
- CountryRepublic of Korea
- Language:English
- Abstract: Varicella zoster virus (VZV) is a human neurotropic alphaherpesvirus that causes chickenpox (varicella) in children. VZV reactivation may lead to neurological complications, including transverse myelitis. However, transverse myelitis caused by VZV reactivation is rare in immunocompetent patients. Herein, we report a case of transverse myelitis caused by VZV in an immunocompetent older patient, and confirmed this case by polymerase chain reaction. A 79-year-old woman visited our service with complaints of weakness in the right lower leg, generalized vesicular eruptions, and throbbing pain in the right flank for ten days. Spine MRI showed transverse myelitis in the thoracic spine at level T4–T11. The patient was treated with acyclovir and her neurological functions improved, except for sensory impairment below level T10. For older patients, early and aggressive antiviral treatment against VZV may be necessary even though these patients are immunocompetent.
