Effect of TCTS on experimental endometriosis of rats.
- Author:
Min HONG
1
;
Yong-qing HUA
;
Li YU
;
Xiao-yu SUN
;
Xiao-dong LI
;
Quan ZHU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Cinnamomum zeylanicum; chemistry; Curcuma; chemistry; Drug Combinations; Drugs, Chinese Herbal; isolation & purification; pharmacology; Endometriosis; blood; pathology; Endometrium; pathology; Estradiol; blood; Female; Follicle Stimulating Hormone; blood; Luteinizing Hormone; blood; Phytotherapy; Plants, Medicinal; chemistry; Prunella; chemistry; Rats; Rats, Sprague-Dawley; Uterine Diseases; blood; pathology
- From: China Journal of Chinese Materia Medica 2003;28(1):69-72
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effect of TCTS on endometriosis rats.
METHODOn the model of surgical induced rat endometriosis, weight and pathological changes of endometrial transplant and serum hormones were observed.
RESULTWeight of endometrial transplants was reduced by TCTS 11.2 g.kg-1 and 22.5 g.kg-1 and transplants of TCTS treated rat showed poorly developed epithelium, thinner stroma, fewer stromal cells and glands. At the same time elevated serum E2, FSH and LH were reduced by TCTS.
CONCLUSIONTCTS can inhibit the growth of endometrial transplants, which is related with serum hormone, especially E2.
