Advances in studies on chemical constituents of Senecio.
- Author:
Bin WU
1
;
Li-jun WU
Author Information
1. Natural Medicine Research Lab., Shenyang Pharmaceutical University, Shengyang 110016, Liaoning, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Anti-Bacterial Agents;
pharmacology;
Antineoplastic Agents, Phytogenic;
pharmacology;
Chromatography, High Pressure Liquid;
methods;
Humans;
Molecular Structure;
Plants, Medicinal;
chemistry;
Pyrrolizidine Alkaloids;
chemistry;
isolation & purification;
pharmacology;
Senecio;
chemistry;
Sesquiterpenes;
chemistry;
isolation & purification;
pharmacology;
Sesquiterpenes, Eudesmane;
chemistry;
isolation & purification
- From:
China Journal of Chinese Materia Medica
2003;28(2):97-100
- CountryChina
- Language:Chinese
-
Abstract:
The large cosmopolitan genus Senecio, a perennial medicinal herb of the family compositae, has been utilized as a anthmicrobial agent. A variety of pyrrolizidine alkaloids and furanoeremophilanes are widespread in the genus Senecio, which are responsible for the hepatotoxic and carchnogenic effects. Some of them have been screened for anti-tumour activity, but their liver toxicity renders their use in chemotherapy. This article reviews the recent advances in chemical constituents, identification methods and pharmacological activities of it.
