Studies on the new triterpenoid saponin of the aerial part of Cimicifuga foetida.
- Author:
Rui-le PAN
1
;
Di-hua CHEN
;
Jian-yong SI
;
Xiao-hong ZHAO
;
Lian-gang SHEN
Author Information
- Publication Type:Journal Article
- MeSH: Cimicifuga; chemistry; Galactosides; chemistry; isolation & purification; Lanosterol; analogs & derivatives; chemistry; isolation & purification; Molecular Structure; Plant Components, Aerial; chemistry; Plants, Medicinal; chemistry; Saponins; chemistry; isolation & purification; Triterpenes; chemistry; isolation & purification
- From: China Journal of Chinese Materia Medica 2003;28(3):230-232
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo find new active constituents from the aerial part of Cimicifuga foetida.
METHODVarious column chromatographic techniques were used for the isolation and purification of the principles. The structures were elucidated on the basis of spectral data and chemical evidences.
RESULTFour 9,19-cycloartane triterpenoid saponins were obtained and identified as Cimifoetiside III (25-anhydrocimigenol-3-O-beta-D-galactopyranoside, 1), 25-O-acetyl-cimigenol xylopyranoside (2), 25-O-acetyl-cimigenol galactopyranoside (3), 7 beta-hydrocimigenol xylopyranoside (4).
CONCLUSIONCompound 1 is new and compound 4 was isolated from this plant for the first time.
