Evaluating the left ventricular diastolic function of diabetes mellitus patients using dual-gate Doppler.
- Author:
Jiani LIU
;
Liping CHEN
;
Xiaoling ZHANG
;
Yanwen SHANG
;
Fang WANG
;
Hong TANG
- Publication Type:Journal Article
- MeSH:
Case-Control Studies;
Diabetes Mellitus, Type 2;
physiopathology;
Diastole;
Echocardiography, Doppler;
Humans;
Hypertension;
Mitral Valve;
Regression Analysis;
Reproducibility of Results;
Ventricular Dysfunction, Left;
Ventricular Function, Left
- From:
Journal of Biomedical Engineering
2015;32(1):163-167
- CountryChina
- Language:Chinese
-
Abstract:
To evaluate the value of left ventricular diastolic function in type 2 diabetes mellitus (DM) using dual-gate Doppler and relative factors, we included 50 non-obesity and hypertension-free DM patients into the controlled group in the study along with 48 age-and-gender-matched healthy volunteer subjects. The peak early diastolic velocity (E), peak later diastolic velocity (A), deceleration time (DT), anterior mitral annulus diastolic peak velocity (e') , isovolumic relaxation time (IVRT), E/A, E/e', Tei index and T(E-e), were measured with dual-gate Doppler. 20 subjects were randomly selected for repetitive analysis. Study showed statistical difference in E/A, DT, e', E/e', IVRT, Tei index and T(E-e), between the two groups (P < 0.05). Linear regression analysis showed positive correlation between T(E-e), and IVRT, course of DM patients and T(E-e), (Beta = 0.295, P = 0.020), and HbA1c control level and T(E-e), (Beta = 0.399, P = 0.010). Repeated analysis showed good reproducibility for both within and between groups. Dual-gate Doppler has clinical value in evaluating left ventricular diastolic function in type 2 diabetes mellitus patients. The course of type 2 diabetes mellitus patients and HbA(1C) control level were both closely related with left ventricular diastolic function.
