Study on the regulatory effects of mechano growth factor on soft tissue repair.
- Author:
Can YU
;
Yongqiang SHA
;
Pan GUO
;
Yimei CHEN
;
Lucy Wanjiru NJUNGE
;
Yonggang LU
;
Li YANG
- Publication Type:Journal Article
- MeSH:
Cell Differentiation;
Cell Proliferation;
Humans;
Insulin-Like Growth Factor I;
physiology;
Soft Tissue Injuries;
Wound Healing
- From:
Journal of Biomedical Engineering
2015;32(1):235-239
- CountryChina
- Language:Chinese
-
Abstract:
Mechano growth factor (MGF) is an autocrine/paracrine factor and sensitive to mechanical stimulation. MGF can be highly expressed in various soft tissues under physical stimuli, biochemistry stimuli or in damaged situation. MGF may "compensate" the stress for tissue in the processing of tissue repair. MGF can effectively accelerate the repair of the soft tissue by promoting the proliferation, migration and differentiation of cells. This paper summarizes the MGF expressions in different soft tissues and their functions in soft tissue repair. The paper also discusses current problems and challenges in using MGF to repair the soft tissue.
