Studies on the chemical constituents of Dendrobium fimbriatum.
- Author:
Zhi-ming BI
1
;
Zheng-tao WANG
;
Luo-shan XU
;
Guo-jun XU
Author Information
- Publication Type:Journal Article
- MeSH: Anthraquinones; chemistry; isolation & purification; Antineoplastic Agents, Phytogenic; chemistry; isolation & purification; pharmacology; Cell Division; drug effects; Dendrobium; chemistry; Emodin; analogs & derivatives; chemistry; isolation & purification; Heterocyclic Compounds, 4 or More Rings; chemistry; isolation & purification; pharmacology; Humans; Lactones; chemistry; isolation & purification; pharmacology; Molecular Structure; Plants, Medicinal; chemistry; Stomach Neoplasms; pathology; Tumor Cells, Cultured
- From: Acta Pharmaceutica Sinica 2003;38(7):526-529
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo investigate the chemical constituents of Dendrobium fimbriatum Hook.
METHODSVarious chromatographic techniques were employed for isolation and purification of the constituents. The structures were elucidated by IR, MS, 1HNMR, 13CNMR and 2D-NMR.
RESULTSEight compounds were obtained and identified by spectral analysis as fimbriatone, confusarin, crepidatin, physcion, rhein, ayapin, scopolin methyl ether and n-octacostyl ferulate.
CONCLUSIONFimbriatone is a new compound, physcion and rhein are firstly isolated from Genus Dendrobium. The others are found from this species for the first time. Fimbriatone showed potential inhibitory effects on BGC cell line.
