Meta analysis on the effectiveness of inactivated influenza vaccine
10.3760/cma.j.issn.0254-6450.2009.04.015
- VernacularTitle:流感灭活疫苗在中国应用效果的Meta分析
- Author:
Yi XING
1
;
Min LIU
Author Information
1. 北京大学医学部
- Keywords:
Inactivated influenza vaccine;
Vaccine effectiveness;
Meta analysis
- From:
Chinese Journal of Epidemiology
2009;30(4):368-370
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the effectiveness of inactivated influenza vaccines (IIV).Methods We did a Meta analysis on IIV effectiveness with papers published during March 1998 and May 2008 in Chinese journals, using fixed model or random model according to the heterogeneity of the studies. Results A total number of 13 studies were included, of which 11 were cohort studies and 2 were randomized controlled trials. Through Meta analysis on cohort studies regarding the effectiveness against influenza like illness (ILI) ,we noticed that the effectiveness of the vaccine was 66% (95%CI:51%-76 % ) in children and adolescents, but 47 % (25 %-63 % ) in adults, and 53 % (20%-72%) in the elderly. Conclusion IIV was effective in protecting against influenza like illness.
