Epidemiological characteristic of first case of locally identified A/H1N1 secondary cases caused by imported source of infection in China
10.3760/cma.j.issn.0254-6450.2009.07.009
- VernacularTitle:国内首起本地感染甲型H1N1流感疫情的流行病学分析
- Author:
Zhi-Cong YANG
1
;
Tie-Gang LI
;
Yu-Fei LIU
;
Xin-Wei WU
;
Jun YUAN
;
Chao-Jun XIE
;
Kui-Biao LI
;
Li-Yun JIANG
;
Yi-Yun CHEN
;
Xin-Wu MAO
;
Hai-Lin LI
;
Liu-Hua ZHAN
;
Xiao-Ling XIAO
;
Jian-Ping LIU
;
Ji-Chuan SHEN
;
Wen-Feng CAI
;
Ming WANG
Author Information
1. 广州市疾病预防控制中心
- Keywords:
A/H1N1;
Autochthonous infection;
Epidcmiologic feature
- From:Chinese Journal of Epidemiology
2009;30(7):684-686
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the first locally identifcd A/HINI secondary cases outbreak in China. Methods Interview and field investigation were integrated to describe the whole process of transmission on each case and to illustrate the relationships between the onset of the disease and the retated factors. Results Two contact persons appearanced fever and whose throat swabs were tested positive to H1N1 viral nucleic acid. The two had a history of contact in a short distance with the initial imported case without any protective measure in the poor air ventilation. The patients clinical situation was slight. The incubation was between 37 hours and 57 hours. No other new case was found after intervention as isolation and antisepsis were taken. Conclusion This event was proved to be an outbreak of local A/H1N1 secondary cases caused by the imported case. The main mode of transmission was personal contact in a short distance without protection, through air and droplet. The locus with poor air ventilation was high risk place. Contact persons should be observed seven days and tested continuously.Infectivity and pathogenicity of the A/H1N1 virus were limited and appeared weakened by generations. Patient's condition was related with persistence and frequency of contact with the infection sources. Enhancing management of contact persons, health education, early diagnose, early treatment and early insulation were effective measures of controling and prenventing the spread A/H1N1.
