Neuron-specific Enclose and Myelin Basic Protein in Cerebrospinal Fluid of Patients with First Episode Schizophrenia
- Author:
Shuying LI
1
;
Hanrong WU
;
Huirong GUO
;
Zheng ZHAO
Author Information
1. 华中科技大学同济医学院
- Keywords:
schizophrenia;
eerebrospinal fluid;
neuron specific enolase;
myelin basic protein
- From:
Journal of Huazhong University of Science and Technology (Medical Sciences)
2006;26(2):228-230
- CountryChina
- Language:Chinese
-
Abstract:
In order to study whether patients with schizophrenia have cerebral injury, neuron-specific enolase (NSE) and myelin basic protein (MBP)in cerebrospinal fluid (CSF) of 33 patients with first episode schizophrenia and 9 from the control group were determined by double antibody sandwich enzyme immunoassay method. The results showed that there was significant difference in the NSE contents between the experimental group and control group (P＜0.01). The NSE contents in CSF in the experimental group were positively correlated with MBP in schizophrenia patients (P＜0.05). These findings suggested that patients with schizophrenia had cerebral injury.
