Association of the serum testosterone level with metabolic syndrome in men.
- Author:
Guo-feng SUN
1
;
Yi WANG
;
Wen-feng ZHAO
;
Yan-qun NA
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Blood Glucose; analysis; Blood Pressure; Case-Control Studies; Cholesterol, HDL; blood; Humans; Male; Metabolic Syndrome; blood; physiopathology; Middle Aged; Testosterone; blood; Triglycerides; blood; Waist Circumference
- From: National Journal of Andrology 2011;17(2):140-142
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the association of the serum testosterone (T) level with metabolic syndrome (MS).
METHODSWe enrolled in this investigation 1,006 men aged 30-60 years in Beijing and obtained the data on their blood pressure (BP), waist circumference (WC), fasting blood glucose (FBG), serum triglycerides (TG), high density lipoprotein-cholesterol (HDL-C) and serum testosterone (T). The men were divided into an MS group and a non-MS (NMS) group based on The Chinese Adult Dyslipidemia Prevention Guide 2007. The results were compared and analyzed.
RESULTSThere was no statistically significant difference between the ages of the two groups (P >0.05). Systolic BP (SBP), diastolic BP (DBP), WC, FBG and TG were significantly higher, while serum T and HDL-C remarkably lower in the MS than in the NMS group (P <0.001). The serum T level was markedly decreased with the increase of MS components (P <0.01). Both Pearson's correlation coefficients and multiple linear regression analyses showed that the serum T level was negatively correlated with age, WC, SBP and TG (P < 0.05).
CONCLUSIONLow serum T level may predict the development of MS in men.
