Intracardiac Thrombosis Involving All Four Cardiac Chambers after Extracardiac Membranous Oxygenation Associated with MTHFR Mutations.
10.5090/kjtcs.2016.49.3.207
- Author:
Bong Jun KIM
1
;
Seung Hwan SONG
;
Yu Rim SHIN
;
Han Ki PARK
;
Young Hwan PARK
;
Hong Ju SHIN
Author Information
1. Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Congenital Heart Disease Center, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Korea. babymedi@naver.com
- Publication Type:Case Report
- Keywords:
Myocarditis;
Extracorporeal membrane oxygenation;
Thrombosis;
Methylenetetrahydrofolate reductase
- MeSH:
Ambulatory Care Facilities;
Aortic Valve;
Arm;
Echocardiography;
Emergencies;
Extracorporeal Membrane Oxygenation;
Follow-Up Studies;
Heart;
Humans;
Infant;
Male;
Methylenetetrahydrofolate Reductase (NADPH2);
Myocarditis;
Oxygen*;
Thrombectomy;
Thrombosis*
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2016;49(3):207-209
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 4-month-old boy diagnosed with acute myocarditis was treated with extracorporeal membrane oxygenation (ECMO). Follow-up echocardiography eight hours after ECMO revealed intracardiac thrombosis involving all four heart chambers. Because of the high risk of systemic embolization due to a pedunculated thrombus of the aortic valve, we performed an emergency thrombectomy. After the operation, the patient had a minor neurologic sequela of left upper arm hypertonia, which had almost disappeared at the last outpatient clinic two months later. He was diagnosed with a major mutation in MTHFR (methylenetetrahydrofolate reductase), which is related to thrombosis.