Factors Affecting Prognosis in Early Gastric Cancer.
10.5230/jkgca.2009.9.4.238
- Author:
Ki Bin HAN
1
;
You Jin JANG
;
Jong Han KIM
;
Sung Soo PARK
;
Seong Heum PARK
;
Seung Ju KIM
;
Young Jae MOK
;
Chong Suk KIM
Author Information
1. Department of Surgery, College of Medicine, Korea University, Seoul, Korea. chongsuk@korea.ac.kr
- Publication Type:Original Article
- Keywords:
Early gastric cancer;
Prognostic factors;
Lymph node metastasis
- MeSH:
Humans;
Lymph Node Excision;
Lymph Nodes;
Multivariate Analysis;
Neoplasm Metastasis;
Prognosis;
Recurrence;
Retrospective Studies;
Risk Factors;
Stomach Neoplasms
- From:Journal of the Korean Gastric Cancer Association
2009;9(4):238-245
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Treatment strategies for early gastric carcinoma (EGC) should be based on achieving a complete cure, but clear indications for limited surgery have not been established. We investigated surgical outcomes for early gastric cancer to determine the optimal? treatment strategy for EGC. MATERIALS AND METHODS: Subjects included 881 patients who underwent curative surgery for EGC between 1986 and 2003. Retrospective uni & multi-variate analysis for prognostic factors, factors affecting lymph node metastasis, and risk factors for cancer recurrence were analyzed. RESULTS: In multivariate survival analyses, age, operation method, macroscopic appearance and lymph node stage proved to be independent prognostic factors. Lymph node metastasis, depth of tumor invasion, tumor size, lymphatic and venous invasion were also significant risk factors in multivariate analyses. In multivariate analyses for cancer recurrence, depth of tumor invasion and lymph node metastasis proved to be significant risk factors. CONCLUSION: Appropriate surgical treatment with lymph node dissection is necessary for EGC patients with risk factors for lymph node metastasis.
