Influence of Shenfu Injection on the quality of life of lung cancer patients receiving chemotherapy.
- Author:
Shun-qin LONG
1
;
Gui-ya LIAO
;
Wen-feng HE
;
Bin WANG
;
Hong DENG
;
Hai-bo ZHANG
;
Xiao-shu CHAI
;
Jiao-zhi CAI
;
Wan-yin WU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; adverse effects; therapeutic use; Carcinoma, Non-Small-Cell Lung; drug therapy; Cisplatin; administration & dosage; Drugs, Chinese Herbal; therapeutic use; Female; Humans; Lung Neoplasms; drug therapy; Male; Middle Aged; Nausea; prevention & control; Paclitaxel; administration & dosage; Phytotherapy; Quality of Life; Surveys and Questionnaires; Vinblastine; administration & dosage; analogs & derivatives; Vomiting; prevention & control
- From: Journal of Southern Medical University 2011;31(12):2090-2092
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the influence of Shenfu Injection (SHF) on the quality of life of patients with advanced non-small cell lung cancer (NSCLC) receiving chemotherapy.
METHODSA total of 133 patients with NSCLC receiving at least two cycles of chemotherapy with taxol plus cisplatin (TP)/vinorelbine plus cisplatin (NP) or gemcitabine plus cisplatin (GP) were randomized into SHF pre-treatment group (with SHF given only in the first cycle) and SHF post-treatment group (with SHF given only in the second cycle). The Quality of Life Questionnaire-Core 30 (QLQ-C30) and the Functional Living Index-Cancer (FLIC) were used to evaluate the quality of life of the patients after the treatments.
RESULTSBoth of the groups showed improved quality of life after the treatments (P<0.01), but the improvements were more obvious in SHF pre-treatment group (P<0.05). SHF showed favorable effects in relieving such adverse effects as fatigue, nausea, vomiting and diarrhea associated with the chemotherapy.
CONCLUSIONSHF can improve the quality of life in NSCLC patients receiving chemotherapies.
