Nanobody: a Novel Molecular Imaging Tool.
- Author:
Weidang LIU
;
Weifeng LIU
- Publication Type:Journal Article
- MeSH:
Humans;
Immunoglobulin Heavy Chains;
Molecular Imaging;
methods;
Molecular Probes;
Nanotechnology
- From:
Chinese Journal of Medical Instrumentation
2015;39(6):423-426
- CountryChina
- Language:Chinese
-
Abstract:
Nanobodies are derived from the variable domain of the heavy-chain antibodies (HCAbs) that occur naturally in the serum of camels. Using nanobody-based probes, several imaging techniques such as radionuclide-based, optical and ultrasound have been employed for visualization of target expression in various disease models. Combined with application and clinical data of nanobody in molecular imaging in recent years, this paper introduces its application in the diagnosis of diseases and the future development as a novel molecular imaging tool.
