Development of ion-sensitivity in-situ gel.
- Author:
Long DAI
1
Author Information
1. Shandong University of Traditional Chinese Medicine, Jinan 250355, China. dailongdailong@263.net
- Publication Type:Journal Article
- MeSH:
Alginates;
chemistry;
Animals;
Drug Administration Routes;
Drug Delivery Systems;
methods;
Gels;
chemistry;
Humans;
Ions;
chemistry;
Medicine, Chinese Traditional;
Polysaccharides, Bacterial;
chemistry
- From:
China Journal of Chinese Materia Medica
2009;34(5):515-518
- CountryChina
- Language:Chinese
-
Abstract:
The recent research papers in ion-sensitivity in-situ gel were reviewed on the following aspects: the characteristics of the gel, the polymer, preparation technology as well as the applications of optical, nasal, and oral route of administration. The solution-gel property of transformation of in-situ gel, which has simple preparation, convenient operation, strong affinity and enough retention time with affected part, especially with mucosa. The recent research advances in ion-sensitivity in-situ gel were mainly reviewed from the following aspects: the characteristics of the gel, the polymer, preparation technology as well as the applications of optical, nasal, and oral route of administration. The present problems of in-situ gel and prospective applications in traditional Chinese medicine were also discussed.
