PI-3K/Akt/GSK-3beta signaling cascades stimulated by insulin like growth factor-I contribute to multiple myeloma cells proliferation and survival.
- Author:
Meng-chang WANG
1
;
Xue-de FU
;
Man-xiang LI
Author Information
1. Department of Hematology, First Hospital of Xi'an Jiaotong University, Xi'an 710061, China. swallow3956@yahoo.com
- Publication Type:Journal Article
- MeSH:
Cell Line, Tumor;
Cell Proliferation;
drug effects;
Cell Survival;
drug effects;
Glycogen Synthase Kinase 3;
physiology;
Glycogen Synthase Kinase 3 beta;
Humans;
Insulin-Like Growth Factor I;
pharmacology;
Interleukin-6;
physiology;
Multiple Myeloma;
pathology;
Phosphatidylinositol 3-Kinases;
physiology;
Proto-Oncogene Proteins c-akt;
physiology;
Signal Transduction;
drug effects
- From:
Chinese Medical Journal
2006;119(14):1226-1229
- CountryChina
- Language:English
