The effect of overtraining on human sperm chromatin structure.
- Author:
Xiao-ping DING
1
;
Su-wen YAN
;
Ning ZHANG
;
Li ZHANG
;
Jie TANG
;
Hai-ou LU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Chromatin; genetics; metabolism; DNA Fragmentation; Exercise; physiology; Humans; Male; Sperm Motility; physiology; Spermatozoa; cytology; metabolism
- From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2003;21(4):260-262
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo identify the effects of overtraining on human sperm DNA.
METHODSMolecular epidemiological investigation of 249 men from different groups (training and non-training) was carried out by using flow cytometer to detect the integrity and damage of in situ DNA of sperm nucleus, and sperm chromatin structure assay was performed.
RESULTSThe average COMPalpha(t) in training group was 11.02% while that in control group was 5.90% (P < 0.01). COMPalpha(t) was significantly correlated with sperm activity (r = 0.41, P < 0.05).
CONCLUSIONOvertraining could induce sperm DNA injury and affect sperm activity, thus to decrease the potentiality of reproduction.
