Efficacy of maduxin in the treatment of slaked lime burn
- Author:
Tuan Ngoc Nguyen
- Publication Type:Journal Article
- Keywords:
burn
- MeSH:
burns;
therapeutics
- From:Journal of Practical Medicine
1998;348(5):10-13
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Maduxin ointment is extracted from leaves and seeds of the Madhuca pasquieri H. J. Lam, Sapotaceae family and has been applied in burn treatment in Vietnam since 1987. We studied the effects of Maduxin at slaked lime burn wounds - a frequent type of burn in Vietnam - in comparison with the effect of sliversulfadiazin in burn treatment. Our study was carried out on 91 slaked lime burn patients who were treated at the Vietnam National Institute of Burn from November 1994 to October 1997. The results showed that Maduxin ointment transferred wet eschar to dry eschar shortened the treatment of III - level burn to 17.8 days from 19.50days in the control group. After 2 weeks of treatment, Maduxin limited the appearance of P. aeruginosa and S. aureus, reduced the number of microbacteria in the surface of the wounds to the similar number of that in the control group. The number of fibrocytes, fibroblastes in the burn wounds treated with Maduxin ointment increased significantly after 14 days and the mucopolysaccharide was created after 7-15 days at a higher level than that in the control group.
