Adverse drug reactions induced by Mailuoning injection: literature review on 162 cases.
- Author:
Gui-Ying XING
1
;
Chang-Yu LI
;
Yuan-Xiao YANG
Author Information
1. Zhejiang Chinese Medicine University, Hangzhou 310053, China.
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Age Distribution;
Aged;
Aged, 80 and over;
Anaphylaxis;
chemically induced;
epidemiology;
pathology;
Child;
Dose-Response Relationship, Drug;
Drug-Related Side Effects and Adverse Reactions;
epidemiology;
mortality;
Drugs, Chinese Herbal;
administration & dosage;
adverse effects;
Female;
Humans;
Injections;
Male;
Middle Aged;
Sex Distribution;
Time Factors
- From:
China Journal of Chinese Materia Medica
2008;33(11):1322-1326
- CountryChina
- Language:Chinese
-
Abstract:
To understand the adverse drug reaction (ADR) induced by Mailuoning injection. 162 ADRs due to the drug were retrieved from national medical journals of 1988-2007 for statistics. It was shown that there was no relationship between ADR and dosage, but ADR appeared mostly in middle-aged and old groups, and more in male than in female. The occurrence of ADR was commonly within 30 min after injection. It involved injuries of various systems and organs. As for the 123 cases of allergy, 38 were anaphylactic shock (accounting for 23.46%), two people died. ADR characterized by immediate type on initial use and tachy type. It should be paid more attention to the Mailuoning injection for the immediate hypersensitivity reaction (such as anaphylactic shock).
