Roller compaction research of Banlangen effervsce tablets.
- Author:
Xiao-jian LUO
1
;
Hong-liang XIN
;
Xiao-yong RAO
;
Zhi-qiang XIAO
;
Li-li GAO
;
Ting-ting SUN
;
Xin-rui LI
Author Information
- Publication Type:Journal Article
- MeSH: Analysis of Variance; Drug Compounding; methods; Drugs, Chinese Herbal; chemistry; Pressure; Tablets; Time Factors; Water; chemistry
- From: China Journal of Chinese Materia Medica 2008;33(12):1402-1406
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the conditions and parameters of roller compaction of Banlangen effervsce tablet.
METHODThe experimentation adopts L9 (3(4)) orthogonal experiment to study the conditions and parameters of roller compaction of Banlangen effervsce tablet; studied factors that included roller pressure, roller speed and moisture content of power, which influence the result of granule yield and granule friability.
RESULTThe optimal technique is: roller pressure at 1.5 MPa; roller speed at 15 Hz; moisture content of power at 1.5%.
CONCLUSIONThe study of roller compaction technique of Banlangen effervsce tablets provides some technicial consults of its research and production.
