Distribution of HLA - DRB1 & DQB1 alleles in Muong ethnic of Viet Nam.
- Author:
An Trieu Vu
- Publication Type:Journal Article
- Keywords:
allele
- MeSH:
HLA-DRB1 antigen;
Vietnam;
Alleles;
Ethnic Groups
- From:Journal of Medical Research
2002;20(4):8-14
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The distribution of 30 HLA-DRB1 alleles in 85 individuals and 10 HLA-DQB1 alleles in 91 muong populations respectively was studied and compared with those of 8 other Asian populations, including kinh population (103 people), a major ethnic of Viet Nam. The difference was observed in some HLA alleles between the muong and kinh ethnics, the most striking presented in HLA-DQ1*0502 allele (frequency of 48%) in the muongs and in DRB1*1202 in the kinhs. In term of genetic distance, our data support a close relationship between muong, Buyi and Dai Lue, another Southern Chinese ethnic group. conversely, these three populations are distant from North Chinese. This was discussed basing on the ethnic relation.