Long-term results of selective vagotomy plus antrectomy in treatment of duodenal ulcer.
- Author:
Xingjiang WU
1
;
Ning LI
;
Jianming HAN
;
Fukun LIU
;
Zhe XU
;
Jieshou LI
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Digestive System Surgical Procedures; Duodenal Ulcer; surgery; Female; Humans; Male; Pylorus; Treatment Outcome; Vagotomy, Proximal Gastric
- From: Chinese Journal of Surgery 2002;40(11):834-837
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo study the long-term results of selective vagotomy plus antrectomy in treatment of duodenal ulcer.
METHODSOne hundred and ninety-three patients with duodenal ulcer were subjected to selective vagotomy plus antrectomy from November 1977 to November 2001. These patients included 28 patients with refractory ulcer, 112 with recurrent bleeding, 41 with pylori obstruction, and 12 with duodenal and gastric ulcer.
RESULTSBAO, IMAO, PMAO and serum gastrin were decreased significantly after an 1 - 24-year follow-up after selective vagotomy plus antrectomy. The characteristics of inhibitory secretive were observed in parietal cells. Follow-up after operation for 1 - 10 years and 11 - 24 years showed that 95.60% and 96.61% of patients belonged to Visick grade I and II, and 4.40% and 3.39% of patients belonged to Visick grade III, respectively. No ulcer recurrence was seen during the 1 - 24 year follow-up after the operation.
CONCLUSIONSV + A is an effective method for duodenal ulcer, especially for complicated duodenal ulcer, with permanent reduction of gastric acid and no recurrence.