Nitric oxide and cytokine levels in the seminal plasma of infertile men.
- Author:
Hong WU
1
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Cytokines; metabolism; Humans; Infertility, Male; metabolism; Interleukin-6; metabolism; Interleukin-8; metabolism; Male; Middle Aged; Nitric Oxide; metabolism; Semen; metabolism; Tumor Necrosis Factor-alpha; metabolism
- From: Chinese Journal of Surgery 2002;40(11):858-859
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the effect of nitric oxide (NO), TNF alpha, IL-6, IL-8 on the pathogenesis of infertile men.
METHODSNO, TNF alpha, IL-6 and IL-8 levels were assayed in 80 infertile men and 26 normal men.
RESULTSThe levels of NO, TNF alpha, IL-6 and IL-8 in infertile men were all significantly higher than those in controls (P < 0.01 or P < 0.05). NO was positively correlated with TNF alpha, IL-6 and IL-8 (P < 0.01).
CONCLUSIONNO, TNF alpha, IL-6 and IL-8 might play an important role in the pathogenic process of infertile.
