Immunologic pathogenesis of multiple sclerosis.
10.1007/s12264-008-2429-8
- Author:
Min-Fang GUO
1
;
Ning JI
;
Cun-Gen MA
Author Information
1. Institute of Brain Science, Shanxi Datong University, Datong, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Autoantibodies;
immunology;
Humans;
Models, Biological;
Multiple Sclerosis;
etiology;
immunology;
pathology;
Myelin Basic Protein;
metabolism
- From:
Neuroscience Bulletin
2008;24(6):381-386
- CountryChina
- Language:English
-
Abstract:
Multiple sclerosis (MS) is an autoimmune disease. The etiology and pathogenesis of MS remain unclear. At present, there are substantial evidences to support the hypothesis that genetics plays a crucial role. The people who have genetic predisposing genes easily develop immune-mediated disorder, probably in conjunction with environmental factors. The aim of this review is to describe recent observations regarding the immunologic pathogenesis of MS.