Follow-up Study of Retreatment TB Patients with Sputum Smear and/or Culture Positive Two Years after They were Declared Cured with First-line Anti-TB Drugs in Shandong Province.

Fang LI; Chun Yan Song; Fei Zhao; Ming Li Liang; Zhi Min Liu; Xiao Yan Guo; Yu Wang; Guang Xue HE

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Follow-up Study of Retreatment TB Patients with Sputum Smear and/or Culture Positive Two Years after They were Declared Cured with First-line Anti-TB Drugs in Shandong Province.

Author: Fang LI ¹ ; Chun Yan SONG ¹ ; Fei ZHAO ² ; Ming Li LIANG ¹ ; Zhi Min LIU ¹ ; Xiao Yan GUO ¹ ; Yu WANG ¹ ; Guang Xue HE ³
Author Information

1. Chest Hospital of Shandong Province, Jinan 250013, Shandong, China.
2. National Center for Tuberculosis Control and Prevension, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
3. Science and Technology Department, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Publication Type:Letter
MeSH: Adult; Aged; Aged, 80 and over; Antitubercular Agents; therapeutic use; China; epidemiology; Female; Follow-Up Studies; Humans; Logistic Models; Male; Middle Aged; Recurrence; Risk Factors; Sputum; microbiology; Tuberculosis, Pulmonary; drug therapy; epidemiology; microbiology
From: Biomedical and Environmental Sciences 2015;28(2):152-156
CountryChina
Language:English
Abstract: This study aimed to learn the recurrence rate in the retreatment TB patients with sputum smear and/or culture positive (ss+ and/or c+) two years after they were declared cured, and to explore causes of recurrence in order to improve long-time treatment outcome. 5 cities were selected as research locations. Recurrence of TB was judged by chest X-ray examination together with sputum smear and culture examination. Questionnaire was carried out to collect data on treatment history, demographics and possible risk factors. Chi-square test and logistic regression were conducted using SPSS in this study. As the result, 99 active TB patients were identified and the recurrence rate was 16.67% and irregular medicine and smoking were the causes of the recurrence. The retreatment TB patients with sputum smear and/or culture positive in this study had higher recurrence rate and health education work on regular medication and smoking should be strengthened.