The Benefit Risk Assessment of Consumption of Marine Species Based on Benefit-Risk Analysis for Foods (BRAFO)-tiered Approach.

Yi Xiong Gao; Hong Xia Zhang; Jing Guang LI; Lei Zhang; Xin Wei YU; Jia Lu HE; Xiao Hong Shang; Yun Feng Zhao; Yong Ning WU

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The Benefit Risk Assessment of Consumption of Marine Species Based on Benefit-Risk Analysis for Foods (BRAFO)-tiered Approach.

Author: Yi Xiong GAO ^{1
,

2} ; Hong Xia ZHANG ¹ ; Jing Guang LI ³ ; Lei ZHANG ³ ; Xin Wei YU ⁴ ; Jia Lu HE ⁴ ; Xiao Hong SHANG ³ ; Yun Feng ZHAO ³ ; Yong Ning WU ³
Author Information

1. China National Center for Food Safety Risk Assessment, Key Lab of Food Safety Risk Assessment, Ministry of Health, Beijing 100021, China
2. National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
3. China National Center for Food Safety Risk Assessment, Key Lab of Food Safety Risk Assessment, Ministry of Health, Beijing 100021, China.
4. Zhejiang Provincial Key Laboratory of Health Risk Factors for Seafood, Zhoushan Municipal Center of Disease Control and Prevention, Zhoushan 316021, Zhejiang, China.
Publication Type:Journal Article
Keywords: Benefit risk assessment; Benefit-Risk Analysis for Foods (BRAFO); Dioxin-like compound; Methyl mercury; N-3 long-chain polyunsaturated fatty acid
MeSH: Animals; China; Dioxins; analysis; Environmental Pollutants; analysis; Fatty Acids, Omega-3; analysis; Fishes; Humans; Methylmercury Compounds; analysis; Risk Assessment; Seafood; analysis; Species Specificity
From: Biomedical and Environmental Sciences 2015;28(4):243-252
CountryChina
Language:English
Abstract:
OBJECTIVETo assess the net health effect caused by the consumption of specific marine species based on Benefit-Risk Analysis for Foods (BRAFO)-tiered approach.
METHODSTwenty species were collected from the Zhoushan Archipelago, China. Concentrations of n-3 long-chain polyunsaturated fatty acids, methyl mercury (MeHg), and dioxin-like compounds (DLCs) in the samples were analyzed for benefit risk assessment based on BRAFO-tiered approach.
RESULTSBased on the BRAFO-tiered approach, reference scenario (no intake) and alternative scenario (intake of specific species of 200 g/week) were determined. The exposure to MeHg/DLCs via alternative scenario of all studied species did not exceed provisional tolerable weekly/monthly intake. However, the adult population with high DLCs exposure in China would significantly exceed the upper limit of DLCs via an additional alternative scenario of some species such as Auxis thazard. The results of deterministic computation showed that alternative scenario of all studied species generated clear net beneficial effects on death prevention and child IQ gain.
CONCLUSIONThe alternative scenario of all studied species could be recommended to population with average DLCs exposure, and the reference scenario of species with relatively high DLCs concentration could be recommended to population exposed to high DLCs.