Evaluating the Environmental Health Effect of Bamboo-Derived Volatile Organic Compounds through Analysis the Metabolic Indices of the Disorder Animal Model.

Ming GUO; Zheng Qing HU; P James STRONG; Anne-Marie SMIT; Jian Wei XU; Jun FAN; Hai Long WANG

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Evaluating the Environmental Health Effect of Bamboo-Derived Volatile Organic Compounds through Analysis the Metabolic Indices of the Disorder Animal Model.

Author: Ming GUO ¹ ; Zheng Qing HU ¹ ; P James STRONG ² ; Anne-Marie SMIT ³ ; Jian Wei XU ¹ ; Jun FAN ¹ ; Hai Long WANG ⁴
Author Information

1. School of Science, Zhejiang Agricultural & Forestry University, Lin'an Hangzhou 311300, Zhejiang, China.
2. Centre for Solid Waste Bioprocessing, School of Civil Engineering, School of Chemical Engineering, The University of Queensland, St. Lucia 4072, Australia.
3. Scion, Private Bag 3020, Rotorua 3046, New Zealand.
4. School of Environmental and Resource Sciences, Zhejiang Agricultural & Forestry University, Lin'an Hangzhou 311300, Zhejiang, China.
Publication Type:Journal Article
Keywords: Metabolic index; Phyllostachys heterocyla cv. pubescens; Type 2 diabetes; Volatile organic compounds
MeSH: Animals; Bambusa; chemistry; Blood Glucose; metabolism; Diabetes Mellitus, Type 2; metabolism; Disease Models, Animal; Environmental Health; Gas Chromatography-Mass Spectrometry; Lipids; blood; Male; Mice; Mice, Inbred ICR; Volatile Organic Compounds; pharmacology
From: Biomedical and Environmental Sciences 2015;28(8):595-605
CountryChina
Language:English
Abstract:
OBJECTIVETo identify the bamboo VOCs (volatile organic compounds) effect on animal physiological indices, which associated with human health.
METHODSGC/MS was used to analyze the volatile organic compounds from Moso bamboo (Phyllostachys heterocyla cv. pubescens). The effect of VOCs on environmental health was evaluated by analyzing the metabolic indices of the type 2 diabetic mouse model.
RESULTSSpectra of VOC generated by GC/MS were blasted against an in-house MS library confirming the identification of 33 major components that were manually validated. The relative constituent compounds as a percentage of total VOCs determined were alcohols (34.63%), followed by ether (22.02%), aldehyde (15.84%), ketone (11.47%), ester (4.98%), terpenoid (4.38%), and acids (3.83%). Further experimentation established that the metabolic incidence of the disease can be improved if treated with vanillin, leaf alcohol, β-ionone and methyl salicylate. The effects of these VOCs on type 2 diabetes were evident in the blood lipid and blood glucose levels.
CONCLUSIONOur model suggests that VOCs can potentially control the metabolic indices in type 2 diabetes mice. This experiment data also provides the scientific basis for the comprehensive utilization of ornamental bamboos and some reference for other similar study of environmental plants.