Methodology for the assessment of burden of smear-positive pulmonary TB and its infectivity.
- Author:
Qun XU
1
;
Zheng-Lai WU
;
Xiao-Lin LIU
;
Shui-Gao JIN
;
Li-Xing ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Child; China; epidemiology; Cost of Illness; Disabled Persons; Epidemiologic Studies; Female; Humans; Male; Middle Aged; Quality-Adjusted Life Years; Serologic Tests; Tuberculosis, Pulmonary; economics; pathology; transmission
- From: Biomedical and Environmental Sciences 2002;15(1):8-15
- CountryChina
- Language:English
-
Abstract:
OBJECTIVEThe study investigated the burden of smear-positive pulmonary TB and its infectivity using DALY (disability-adjusted life year) as an indicator.
METHODSAn assumed cohort of 2,000 cases was set up based on the age-specific incidence of 794 newly registered smear-positive cases in Beijing in 1994. Prognostic trees and model diagrams of infectivity under natural history and DOTS(directly observed treatment, short-course) strategy were established according to the epidemiological evidence.
RESULTSThe results showed that 29.6% of DALYs would be neglected if the burden caused by the infectivity was not considered.
CONCLUSIONDOTS strategy may reduce 97.3% of the number of potential cases infected, 92.9% of DALYs related to TB-patients themselves, and 99.9% of DALYs caused by TB's infectivity as well.
